organochlorine pesticides residue in breast milk: a systematic review

background: chlorinated pesticides have been used in pest control for several decades in the world. these compounds are still applied in many regions, and their continuous usage has resulted in their bioaccumulation and residue in the food chain. these residues could transfer to food products and accumulate in fat tissues. undoubtedly, the breast milk could be a significant biomarker for estimation of these residues in the human body. this study was conducted to review and compile the results of the studies undertaken in the world which surveyed the organochlorine pesticides residue in breast milk.   methods : a total of 710 national and international articles and texts related to the focused subject were extracted from the virtual databases using the following key words: chlorinated pesticides, residue and breast milk. thirty articles published between 1980 and 2013 were selected and reviewed.   results : the majority of the reviewed articles indicated the presence of two or more organochlorine pesticides in the collected samples of breast milk. based on the reviewed studies, dichlorodiphenyltrichloroethane (ddt) had the highest level of concentration in the collected samples of breast milk. moreover, there was a statistically significant positive correlation between mother’s age, her multiparty and concentration of chlorinated pesticides in breast milk.   conclusion : the organochlorine pesticides are still applied in some developing countries including some regions of iran. thus, it seems essential to inform the community about the adverse effects of this class of pesticides and most importantly the governments should also ban the use of such compounds.